Endocrine Abstracts

A 23 yr old lady was admitted with a generalized tonic clonic seizure in May 2016. Her corrected calcium was 1.47 mmol/l (2.05–2.6 mmol/l) She was initially treated with intravenous calcium gluconate and subsequently switched to oral calcium carbonate tablets and one alphacalcidol tablets once her calcium improved. The patient gave a history of a prior seizure in 2013. At this point she was not investigated for any electrolyte imbalances. She was initially treated with th...

A 72 year old lady presented to endocrine clinic in January 2016 with a history of frequent episodes of feeling increasingly lightheaded, tremulous, sweaty and hungry. All symptoms resolved after eating. Her family doctor had twice documented a capillary glucose lower than 4 mmol/l. Continuous blood glucose monitoring was performed but there were no episodes of hypoglycaemia picked up. She was admitted for a 72 h fast in September 2016. Her capillary blood glucose readings nev...

Introduction: Adrenal medullary hyperplasia (AMH) is a rare syndrome of catecholamine excess.Case: A 59 year old lady known to suffer from hypertension underwent a computed tomography scan of the abdomen as further investigation for unprovoked deep vein thrombosis. This showed a 37 mm right adrenal mass which enhancedheterogeneously with contrast on the porto-venous phase and became homogenously hyperdense on the delayed phase. Findings were not typical ...

A 49 year old male, known to suffer from hypertension, was bein investigated for recurrent occipital headaches. An MR Brain showed a 2.4 cm×2.8 cm×4.2 cm sellar mass with suprasellar extension, optic chiasm compression, infrasellar extension with erosion into the sphenoidal sinus, lateral extension into the left sided cavernous sinus and further extension through the cavernous sinus into the parietal lobe. The tumour contained some cystic areas and moderately enhance...

BackgroundHypercalcaemia is commonly encountered during clinical practice. SCCOHT is a rare ovarian malignancy typically found in young women. In two thirds of patients, it causes a paraneoplastic hypercalcaemia which is usually asymptomatic.Case ReportA thirty-seven-year-old lady, presented to casualty with a one -week history of worsening nausea, vomiting, anorexia, abdominal pain, polydipsia, and polyuria....

A 60-year-old gentleman known to suffer from atrial fibrillation (on warfarin therapy), hypertension and beta-thalassemia trait presented to the endocrine clinic for follow-up of hypothyroidism for which he was started on levothyroxine by his general practitioner about 2 years before. Serial thyroid function tests revealed a progressive reduction in thyroid stimulating hormone (TSH) levels in the setting of a decline in free thyroxine (fT4) levels. The patient denied any histo...

Subclinical hyperthyroidism is defined as low serum thyroid stimulating hormone (TSH) in the setting of normal levels of free T4 (fT4) and free T3 (fT3). Treatment for subclinical hyperthyroidism can be considered when TSH is persistently <0.1, particularly in (i) the presence of hyperthyroid symptoms, (iii) individuals aged >65 years, (iii) the presence of heart disease or osteoporosis. We present a case of a 34-year-old lady who was referred to endocrine outpatient c...

Adrenal insufficiency is a potential life-threatening condition due to lack of cortisol and early diagnosis and management is potentially lifesaving. We describe a 79-year-old lady who presented to the emergency department with new onset confusion, nausea, vomiting and decreased oral intake. Her relatives also reported a one month history of lethargy and weakness. She suffered from gastro-oesophageal reflux for which she was taking Ranitidine, and had a history of total abdomi...

A 38-year-old gentleman was referred to the endocrine clinic after a male fertility test done as part of investigation for infertility showed the following:Volume 4.4 mlTotal sperm number =6.16 Mill/ejacSperm concentration 1.4 Mill/mlProgressive motility 10%Nonprogressive motility 1%Impotence 89%55% sperm vitality<...

A 73-year-old gentleman known to suffer from hypothyroidism was admitted to hospital with severe symptomatic hyponatraemia of 112 mmol/l. He was acutely confused with a GCS of 12/15. He was found to be in urinary retention with 650 ml residual urine post catheterisation. Initially, his serum sodium concentration improved on catheterisation and fluid restriction. The syndrome of inappropriate ADH secretion in the context of urine retention was initially suspected on the bases o...